The Pequot War, a struggle over between the Pequot tribe of Connecticut, who exerted control over eastern Long Island, and the English
New England Colonies, reshaped alliances and power dynamics in the region. The defeat of the Pequots left a void in eastern Long Island's political landscape, who were historically under the influence of the Connecticut Pequots for trade and protection. Indigenous leaders such as
Uncas and
Ninigret, alongside the New England Colonies, vied to fill this vacuum, with the colonists eventually prevailing over their indigenous rivals. In 1639,
Lion Gardiner secured the first purchase of eastern Long Island land, an islet off of present-day
East Hampton.