Official ACC designated rivalry games include the
Virginia–Virginia Tech rivalry and the Virginia–
Louisville series. These two rivalries are guaranteed an annual game in all sports, and a home-and-away series in men's and women's basketball. The Cavaliers competed against the Hokies in the
Commonwealth Challenge and more recently competed in the
Commonwealth Clash, under new rules, for many sports in which they compete head-to-head. The Cavaliers went 2–0 against the Hokies in the
Challenge and 3–2 in the
Clash (5–2 overall). Perhaps the two most significant rivalry games played between the Cavaliers and Hokies were both in men's basketball, in March 2007 and January 2019. In the former, the two teams met with identical 10–4 ACC records and the winner would clinch a share of the regular-season conference championship. UVA won the game 69–56 and took their fifth
of 11 ACC titles. In the latter, No. 4 UVA beat No. 9 Virginia Tech 81–59 in the only game between two AP Top 10 teams in the rivalry's history.