Virginia men's lacrosse, as one of the all-time great NCAA programs, has a championship rivalry with fellow ACC program Syracuse (the Cavaliers and Orange holding 18 NCAA Championships between them) as well as rivalries against Big Ten programs Johns Hopkins and Maryland. The Syracuse and Johns Hopkins rivalries are played out at least once each season (Syracuse played twice in 2021) with the teams often finding themselves facing off a second or third time in the ACC and NCAA tournaments. Virginia women's lacrosse, also a multi-NCAA Championship program, maintains several of those same rivalries.